Hakim R, Tolis G, Goltzman D, Meltzer S, Friedman R "Severe hypercalcemia associated with hydrochlorothiazide and calcium carbonate therapy. Diovan HCT may cause dizziness, light-headedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects. This medication may interfere with certain laboratory tests including parathyroid function possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.
It is not known whether hydrochlorothiazide and valsartan passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. Keep taking this medication even if you feel well. Most people with high blood pressure do not feel sick. This drug is used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This product contains two medications: valsartan and hydrochlorothiazide. Valsartan is an angiotensin receptor blocker ARB and works by relaxing blood vessels so that blood can flow more easily. Hydrochlorothiazide is a "water pill" diuretic that causes you to make more urine, which helps your body get rid of extra salt and water.
Klein MD "Noncardiogenic pulmonary edema following hydrochlorothiazide ingestion. Magil AB, Ballon HS, Cameron EC, Rae A "Acute interstitial nephritis associated with thiazide diuretics. Clinical and pathologic observations in three cases. WebMD User Reviews should not be considered as medical advice and are not a substitute for professional medical advice, diagnosis, or treatment. Never delay or disregard seeking professional medical advice from your physician or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences may be a helpful health information resource but they are never a substitute for professional medical advice from a qualified healthcare provider.
As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. Cough; diarrhea; dizziness; headache; joint or back pain; mild stomach pain; tiredness. Hydrochlorothiazide: a review of its pharmacology, therapeutic efficacy and place in the management of hypertension. Valsartan is an angiotensin receptor blocker ARB and works by relaxing vessels so that can flow more easily. Hydrochlorothiazide is a "water pill" that causes you to make more urine, which helps your body get rid of extra salt and water.
Holwerda NJ, Fogari R, Angeli P, et al. "Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: efficacy and safety compared with placebo and enalapril. Diovan for up to 1 year. Dose-related orthostatic effects were seen in less than 1% of patients. There is no evidence that Diovan prevents or slows dementia in people, but the findings in mice may inspire such a study in people at high risk for Alzheimer's, Pasinetti's team suggests. Cerner Multum, Inc. "UK Summary of Product Characteristics. You may take hydrochlorothiazide and valsartan with or without food. Drinking extra fluids while you are taking Diovan HCT is recommended. Check with your doctor for instructions. If you miss a dose of Diovan, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. This tool does not provide medical advice. Geanon JD, Perkins TW "Bilateral acute angle-closure glaucoma associated with drug sensitivity to hydrochlorothiazide. Eisner EV, Crowell EB "Hydrochlorothiazide-dependent thrombocytopenia due to IgM antibody.
Hyperuricemia may be an important consideration in patients with a history of gout. Hypophosphatemia and low serum magnesium concentrations may occur, but are usually clinically insignificant except in malnourished patients. Some drugs can make rise. If you have to begin with, it can rise to dangerous levels. Many and cold medications contain NSAIDs to relieve pain. NSAIDs may increase your blood pressure. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment. Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource, but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately. The researchers then tested Diovan in mice that were genetically at risk for Alzheimer's disease. Levay ID "Hydrochlorothiazide-induced pulmonary edema. Papademetriou V, Price M, Notargiacomo A, Gottdiener J, Fletcher RD, Freis ED "Effect of diuretic therapy on ventricular arrhythmias in hypertensive patients with or without left ventricular hypertrophy. Reed BR, Huff JC, Jones SK, Orton PW, Lee LA, Norris DA "Subacute cutaneous lupus erythematosus associated with hydrochlorothiazide therapy. maxalt
Tell your doctor if you develop any new symptoms. Diovan HCT should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed. Before using this medication, tell your doctor or pharmacist your medical history, especially of: gout, kidney disease, liver disease, lupus, loss of too much body water and minerals dehydration. Kasiske BL, Ma JZ, Kalil RS, Louis TA "Effects of antihypertensive therapy on serum lipids. Your blood pressure will need to be checked often. It may take 2 to 4 weeks for Diovan HCT to work fully. Do not stop using Diovan HCT or change your dose of Diovan HCT without checking with your doctor. Magil AB "Drug-induced acute interstitial nephritis with granulomas. Hyperkalemia was mainly observed in children with underlying renal disease. Diamond MT "Hyperglycemic hyperosmolar coma associated with hydrochlorothiazide and pancreatitis. This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages. The maximum dose is 320 mg daily. The initial dose after a is 20 mg twice daily. Bell DS "Insulin resistance. An often unrecognized problem accompanying chronic medical disorders. Benz J, Oshrain C, Henry D, Avery C, Chiang YT, Gatlin M "Valsartan, a new angiotensin II receptor antagonist: a double-blind study comparing the incidence of cough with lisinopril and hydrochlorothiazide. Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. 'Multum' is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. efil.info albenza
Side Effects List Diovan side effects by likelihood and severity. What is the dosage for valsartan? Rare cases of interstitial nephritis have been associated with the use of HCTZ. Although HCTZ has been used to treat nephrogenic diabetes insipidus, a case report in which the drug was believed to have caused this condition has been reported. Bronchospasm, dyspnea, and epistaxis have rarely been associated with the use of this drug. Reinus FZ, Weinberger HA, Fischer WW "Medication-induced ulceration of the small bowel. Some medical conditions may interact with Diovan HCT. Those studies were based on patients' medical records, not direct tests of the drugs. So Pasinetti's team headed to their lab to do some experiments. Parodi A, Romagnoli M, Rebora A "Subacute cutaneous lupus erythematosus-like eruption caused by hydrochlorothiazide. An extra patient leaflet is available with Diovan. Talk to your pharmacist if you have questions about this information. Dietz MW "Iatrogenic jejunal ulcer. buy cheap ziprasidone online without a prescription
Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life. This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors. The dosage is based on your medical condition and response to treatment. This drug may also be used to help protect the kidneys from damage due to diabetes. Diovan may cause dizziness, light-headedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects. Do not store in the bathroom. Keep all medications away from children and pets. You may also find NSAIDs in over-the-counter medication for other health problems. Cold medicine, for example, often contains NSAIDs. It's a good idea whenever you purchase an over-the-counter drug to check the label for NSAIDs. Ask your doctor if any NSAID is OK for you to use. However, NSAIDs can make the body retain fluid and decrease function. This medicine is not approved for use by anyone younger than 6 years old. Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions. What happens if I miss a dose? Some may make worse. Appetite suppressants tend to "rev" up the body, increasing both the heart rate and the blood pressure.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication not have serious side effects. Older adults may be more sensitive to the side effects of this drug, especially dizziness and change in the amount of urine kidney problems. If you have high blood pressure, do not use nonprescription products that contain stimulants. These products may include diet pills or cold medicines. Contact your doctor if you have any questions or concerns. Berlin I "Prazosin, diuretics, and glucose intolerance. Tell your doctor if you do not get better or if you get worse for example, your blood pressure readings remain high or increase. Diovan HCT contains a sulfonamide called hydrochlorothiazide, which can cause certain eye problems myopia, angle-closure glaucoma. Your risk may be increased if you are allergic to sulfonamide medicines eg, sulfamethoxazole or to penicillin antibiotics eg, amoxicillin. Untreated angle-closure glaucoma can lead to permanent vision loss. If these eye problems occur, symptoms usually occur within hours to weeks of starting Diovan HCT. Contact your doctor right away if you experience symptoms such as vision changes eg, decreased vision clearness or eye pain. Kiykim A, Altintas E, Sezgin O, et al. "Valsartan-induced hepatotoxicity in a HBs-Ag-Positive patient. Product Information. Diovan valsartan. This information should not be used to decide whether or not to take Diovan or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Diovan. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Diovan. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using Diovan. In rare cases, valsartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have muscle pain, tenderness, or weakness especially if you also have fever, nausea or vomiting, and dark colored urine. differin tablet generic
If you have any questions about Diovan HCT, please talk with your doctor, pharmacist, or other health care provider. If you take cholestyramine or colestipol, ask your doctor or pharmacist how to take it with Diovan HCT. If you have diabetes, do not use hydrochlorothiazide and valsartan together with any medication that contains aliskiren Amturnide, Tekturna, Tekamlo, Valturna. Weir MR, Wright JT, Jr Ferdinand KC, Cook CA, Champion D, Wong S, Jenkins PA, Kong BW "Comparison of the efficacy and metabolic effects of nicardipine and hydrochlorothiazide in hypertensive black men and women. Langtry HD, McClellan KJ "Valsartan hydrochlorothiazide. Store Diovan at room temperature, between 59 and 86 degrees F 15 and 30 degrees C. Store away from heat, moisture, and light. Do not store in the bathroom. If your pharmacist prepares a suspension of Diovan, store as directed by your pharmacist. Keep Diovan out of the reach of children and away from pets. Duarte CG, Winnacker JL, Becker KL, Pace A "Thiazide-induced hypercalcemia. What are the possible side effects of valsartan Diovan? Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Krishna GG, Narins RG "Hemodynamic consequences of diuretic-induced hypokalemia. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. You should not use this medication if you are allergic to valsartan. Before you take valsartan, tell your doctor if you have ever had a to any blood pressure medication. Some medications may interact with medicine. This can prevent either drug from working properly. Since HCTZ may increase total serum cholesterol by 11%, LDL lipoprotein cholesterol by 12%, and VLDL lipoprotein cholesterol levels by 50%, and may reduce insulin secretion, it should be used with caution in diabetic patients and in those with hypercholesterolemia. True glucose intolerance may develop in approximately 3% of patients. It is typically reversible within six months after discontinuation of therapy. Klimiuk PS, Davies M, Adams PH "Primary hyperparathyroidism and thiazide diuretics. zyloprim order online payment
Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal. Take Diovan HCT by mouth with or without food. About FAERS: The FDA Adverse Event Reporting System FAERS is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. Diovan is to be used only by the patient for whom it is prescribed. Do not share it with other people. Check with your pharmacist about how to dispose of unused medicine. Delevett AF, Recalde M "Diuretic-induced renal colic. The mice that drank the Diovan water fared best in the maze test. Continue to take Diovan even if you feel well. Do not miss any doses. Smith BL, Tedeschi A, Lane CD "Pancreatitis with a twist. casodex
It is unknown if valsartan passes into milk. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. This medication may increase your potassium levels. Before using potassium supplements or salt substitutes that contain potassium, consult your doctor or pharmacist. Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Murphy MB, Kohner E, Lewis PJ, Schumer B, Dollery CT "Glucose intolerance in hypertensive patients treated with diuretics: a fourteen-year follow-up. This product may affect your levels. Before using potassium or salt substitutes that contain potassium, consult your doctor or pharmacist. Irons BK, Kumar A "Valsartan-induced angioedema. Our Diovan Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Diabetes patients - Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine. Tsuruoka S, Wakaumi M, Ioka T, et al. "Angiotensin II receptor blocker-induces blunted taste sensitivity: comparison of candesartan and valsartan. This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use and wear protective clothing when outdoors. Read the Patient Information Leaflet if available from your pharmacist before you start taking valsartan and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Mahabir RN, Laufer ST "Clinical evaluation of diuretics in congestive heart failure. A detailed study in four patients. An extra patient leaflet is available with Diovan HCT. Talk to your pharmacist if you have questions about this information. NOS, nausea, renal impairment NOS, syncope, blurred vision, upper abdominal pain and vertigo. If you are using the liquid form of this medication, shake the bottle well for at least 10 seconds before each dose. Miller M, Bachorik PS, McCrindle BW, Kwiterovich PO, Jr "Effect of gemfibrozil in men with primary isolated low high-density lipoprotein cholesterol: a randomized, double-blind, placebo- controlled, crossover study. Severe allergic reactions rash; hives; itching; difficulty breathing or swallowing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; unusual hoarseness; blurred vision; burning, numbness, or tingling; change in the amount of urine produced; chest pain; difficulty swallowing; fainting; irregular heartbeat; muscle pain, weakness, or cramps; shortness of breath; sudden, unexplained weight gain; swelling of the hands, ankles, or feet; symptoms of liver problems eg, dark urine, loss of appetite, pale stools, severe or persistent stomach pain, yellowing of the eyes or skin; symptoms of low blood pressure eg, fainting, light-headedness, severe dizziness; unusual bruising or bleeding. McInnes GT "Clinical advantage of valsartan. Dizziness or lightheadedness may occur as your body adjusts to the medication. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Diovan should not be used in CHILDREN younger than 6 years old; safety in these children has not been confirmed. Read the Patient Information Leaflet if available from your pharmacist before you start taking this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist. If you also take certain drugs to lower your cholesterol bile acid-binding resins such as cholestyramine or colestipol take this product at least 4 hours before or at least 4 to 6 hours after these medications. The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. PREGNANCY and BREAST-FEEDING: Diovan HCT may cause birth defects or fetal death if you take it while you are pregnant. If you think you may be pregnant, contact your doctor right away. Diovan HCT is found in breast milk. Do not breast-feed while taking Diovan HCT. Withdrawal of thiazide therapy for 7 months in 10 of the patients resulted in average reductions of 10% in fasting blood glucose and 25% in 2-hour glucose tolerance test values. A control group was not reported. Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately. safe online leflunomide orders
One of the goals when you take for is to be sure the medication is working effectively. Lab tests, including blood pressure, blood electrolyte levels, heart function, and kidney function, may be performed while you use Diovan. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments. Drink plenty of water each day while you are taking this medicine. Holland GW "Stenosing ulcers of the small bowel associated with thiazide and potassium therapy. Before having surgery, tell your doctor or dentist about all the products you use including prescription drugs, nonprescription drugs, and herbal products. The opinions expressed in WebMD Communities are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. Communities are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. Report any light-headedness or fainting to your doctor immediately. Your risk of light-headedness or fainting may be increased if you experience diarrhea, vomiting, excessive sweating, if you do not drink enough fluids, or if you are on a low-salt sodium diet. If you have diabetes, this product may affect your blood sugar levels. Check your blood sugar levels regularly as directed by your doctor. Your doctor may need to adjust your diabetes medication, exercise program, or diet. Beck ML, Cline JF, Hardman JT, Racela LS, Davis JW "Fatal intravascular immune hemolysis induced by hydrochlorothiazide. Severe sweating, diarrhea, or vomiting can increase the risk for lightheadedness or a serious loss of body water dehydration. Report prolonged diarrhea or vomiting to your doctor. To prevent dehydration, drink plenty of fluids unless your doctor directs you otherwise. Important: The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, blogs, or WebMD Answers are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. At the bottom of the page under Herbal Therapies for High Blood Pressure it does state, "The efficacy and safety of herbal therapies, such as Rauwolfia serpentina snakeroot Stephania tetrandra tetrandrine Panax notoginseng ginseng and Crataegus species hawthorn for treating high blood pressure have not been extensively studied. Because of potential health risks associated with these herbs, it is imperative that you inform your doctor if you plan to use or are already using them. This is even more important if these herbs are used in combination with high blood pressure drugs. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Pasinetti and colleagues pitted 55 drugs against beta-amyloid proteins in test tubes. cardura
Although valsartan may be used to prevent kidney problems or treat people who have kidney problems, it may also rarely cause serious kidney problems or make them worse. Your doctor will check your kidney function while you are taking valsartan. Tell your doctor right away if you have any signs of kidney problems such as a change in the amount of urine. Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose. What happens if I overdose? Biron P "Thiazide-induced pulmonary edema. Grace AA, Morgan AD, Strickland NH "Hydrochlorothiazide causing unexplained pulmonary oedema. These medications may do you more harm than good.
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If your symptoms do not improve or if they become worse, check with your doctor. Take this medication by mouth with or without food as directed by your doctor, usually once daily. If this medication causes you to urinate more frequently, it is best to take it at least 4 hours before your bedtime to prevent having to get up to urinate. This drug may also be used to treat heart failure. Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking hydrochlorothiazide and valsartan. This can lead to very low blood pressure, electrolyte disorders, or kidney failure.
Tell your doctor if you do not get better or if you get worse for example, your remain high or increase. If you have any questions about Diovan, please talk with your doctor, pharmacist, or other health care provider. Product Information. Diovan HCT hydrochlorothiazide-valsartan. This product may affect your potassium levels. Before using potassium supplements or salt substitutes that contain potassium, consult your doctor or pharmacist.
Diffey BL, Langtry J "Phototoxic potential of thiazide diuretics in normal subjects. If you cannot swallow capsules or tablets, ask your doctor or pharmacist about preparing a suspension of Diovan. Brown CW, Deng JS "Thiazide diuretics induce cutaneous lupus-like adverse reaction. Ask your health care provider any questions you may have about how to use Diovan.
Waeber B, Burnier M, Nussberger J, Brunner HR "Experience with angiotensin II antagonists in hypertensive patients. Fine SR, Lodha A, Zoneraich S, Mollura JL "Hydrochlorothiazide-induced acute pulmonary edema. Dehydration, excessive sweating, vomiting, or diarrhea may increase the risk of low blood pressure. Contact your health care provider at once if any of these occur.